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Chayan Kanti Nandi

School of Basic Sciences, Discipline Chemistry

Indian Institute of Technology Mandi India

H.P. 175001

Phone: +91 1905 237917

Mobile: +91 8894377029

E mail: chayan@iitmandi.ac.in

Immediately after completing his PhD from the Indian Institute of Technology Kanpur in 2006, Chayan K Nandi moved to Geothe University Frankfurt am Main Germany for a post doc as an Alexander Von Humboldt Fellow. After spending three years in Germany he moved to Princeton University USA for another post doc. After spending a year at Princeton he joined as an assistant professor in the school of basic sciences, Indian Institute of Technology Mandi in 2010.

The main research area of our group includes the conformational dynamics of macromolecules e.g. protein, DNA using Forster resonance energy transfer. The unique chemical functions of macromolecules, such as proteins or DNA, largely arise from their ability to create distinct local chemical environments, such as binding sites. The complex conformations and chemical compositions of macromolecules produce diverse and highly specific functions. Conformational fluctuations play an important role in macromolecule functions because they change the accessibility and nature of chemically reactive sites. We will mainly focus on the study the fluctuations in the conformations and local chemical environments of macromolecules using Förster resonance energy transfer (FRET). While our experiments focus on studies of macromolecule dynamics in bulk solution FRET, simultaneously the chemical environment sensitive single molecule FRET techniques will be developed for a detail study of the macromolecular conformations, which are not readily available from bulk measurement.

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