Dr. P. C. Ravikumar

Dr. P. C. Ravikumar
Phone : 01905-300044
EMail : ravi[at]iitmandi[dot]ac[dot]in
Address : School of Basic Sciences
IIT Mandi,
(near Bus Stand)
Mandi - 175001
India

Research interests

  • Total Synthesis of Natural Products
  • Synthetic Methodology
  • Asymmetric Synthesis
  • Supramolecular Chemistry
  • Isolation of Natural products from Medicinal Plants

Education

  • PhD (2002-2006) from IISc, Bangalore in the area of Total Synthesis of Sesquiterpene Natural Products
    (Advisor: Prof. A. Srikrishna)
  • MSc (2000-2002) in Organic Chemistry from University of Madras
  • BSc (1997-2000) in Chemistry from University of Madras

Professional Experience

  • Assistant Professor (Sep 2010 to present): School of Basic Sciences, IIT Mandi.
    Post Doctoral Experience
  • 2007-2008 : Duquesne University, USA (with Prof. Fraser F. Fleming)
  • 2009 : Yale University, USA (with Prof. Seth B. Herzon)
    Teaching Experience
  • Spring Semester 2010 : Adjunct Faculty, Duquesne University, USA

Honours And Distinctions

  • Secured All India Second rank with 99.89 percentile score in GATE-2002.
  • Awarded Junior Research Fellowship by the Council for Scientific and Industrial Research (CSIR) in 2002 and subsequently upgraded to Senior Research Fellowship in 2004.
  • Won First Prizes at College and University level Chemistry Quiz Competitions.

Publications

  • Prateep singh sagara , Rajesh chebolu, Ashish bahuguna , P. C. Ravikumar. Hypervalnt Iodine mediated direct one pot transformation of aldehydes to ketones. RSC Adv. 2014, 4, 15011.

  • Christina M. Woo, Shivajirao L. Gholap, Liang Lu, Miho Kaneko, Zhenwu Li, P.C. Ravikumar, and Seth B. Herzon, Development of Enantioselective Synthetic Routes to (–)-Kinamycin F and (–)-Lomaiviticin Aglycon. J. Am. Chem. Soc. 2012, 134 (41), 17262-17273.

  • Lihua Yao, Bhaskar Pitta, P. C. Ravikumar, Matthew Purzycki, and Fraser F.Fleming, Transmissive Olefination Route to Putative "Morinol I" Lignans, J. Org. Chem., 2012, 77(7), 3651–3657.

  • Fraser F. Fleming, Wang Liu, Lihua Yao, Bhaskar Pitta, Matthew Purzycki, P. C. Ravikumar, Alkenenitrile Transmissive Olefination: Synthesis of the Putative Lignan “Morinol I”, Eur. J. Org. Chem., 2011, 34, 6843.

  • Fraser F. Fleming, Lihua Yao, P. C. Ravikumar, Lee Funk and Brian C. Shook, Nirile-Containing Pharmaceuticals: Efficacious role of the Nitrile Pharmacophore, J. Med. Chem., 2010, 53, 7902-7917.

  • Shivajirao L Gholap, Christina M. Woo, P. C. Ravikumar, Seth B. Herzon, Synthesis of the Fully Glycosylated Cyclohexenone Core of Lomaiviticin A, Org. Lett., 2009, 11, 4322-4325.

  • P. C. Ravikumar, Lihua Yao, Fraser F. Fleming, Allylic and Allenic Halide Synthesis via NbCl5- and NbBr5- Mediated Alkoxide Rearrangement. J. Org. Chem., 2009, 74, 7294-7299.For a commentary see: NbCl5/NbBr5-Mediated Alkoxide Rearrangements to Allylic and Allenic Halides. Paul Knochel and Andreas J Wagner, SYNFACTS, 2009, 12, 1394.

  • Fraser F. Fleming, P. C. Ravikumar, Lihua Yao, Direct Conversion of Aldehydes and Ketones to Allylic Halides by a NbX5-[3,3] Rearrangement, Synlett, 2009, 1077-1080.

  • Adusumilli Srikrishna, Ponneri C. Ravikumar, Hema S. Krishnan, The First Total Synthesis of Herbertenone A and Herberteneone B, Synthesis, 2008, 1527-1534.

  • A. Srikrishna, S. Ratna kumar, P. C. Ravikumar, Synthesis of (±)-12-Methoxy Herbertenediol methylether, Synth. Commun., 2007, 37, 4123-4140.

  • A. Srikrishna, R. Ramesh Babu, P. C. Ravikumar, A Regioselective Total Synthesis of Fungal Sesquiterpene (±)-Lagopodin A, Synlett, 2007, 655-657.

  • A. Srikrishna, P. C. Ravikumar, The First Total Synthesis of (±)-γ-Herbertenol, an herbertene isolated from a non-herbertus source, Synthesis, 2007, 65-74.

  • A. Srikrishna, P. C. Ravikumar, Structure revision of HM-3, an aromatic sesquiterpene isolated from phytopatogenic fungus Helicobasidium mompa. First Total Synthesis of HM-3 and HM-4, Tetrahedron, 2006, 62, 9393-9402.

  • A. Srikrishna, B. Vasantha Lakshmi, P. C. Ravikumar, The First Total Synthesis of (±) Lagopodin A, Tetrahedron Lett., 2006, 47, 1277-1281. (This Paper was the Second Most Hottest Paper of the first quarter of 2006)

  • A. Srikrishna, P. C. Ravikumar, Total Synthesis of HM-1 and HM-2, aromatic sesquiterpenes isolated from the phytopatogenic fungus Helicobasidium mompa. Structure revision of HM-2, Tetrahedron Lett., 2005, 46, 6105-6109.

Conferences And Symposia

  • Metallated Nitrile: Preferential SN2 Cyclizations of Allylic Chlorides, Wang Liu, Ping Lu, P. C. Ravikumar and Fraser F. Fleming. 240th American Chemical Society National Meeting, 22nd - 26th Aug 2010, Boston, USA.
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