Isolation of Natural products from Medicinal Plants
PhD (2002-2006) from IISc, Bangalore in the area of Total Synthesis of Sesquiterpene Natural Products (Advisor: Prof. A. Srikrishna)
MSc (2000-2002) in Organic Chemistry from University of Madras
BSc (1997-2000) in Chemistry from University of Madras
Assistant Professor (Sep 2010 to present): School of Basic Sciences, IIT Mandi.
Post Doctoral Experience
2007-2008 : Duquesne University, USA (with Prof. Fraser F. Fleming)
2009 : Yale University, USA (with Prof. Seth B. Herzon)
Spring Semester 2010 : Adjunct Faculty, Duquesne University, USA
Honours And Distinctions
Secured All India Second rank with 99.89 percentile score in GATE-2002.
Awarded Junior Research Fellowship by the Council for Scientific and Industrial Research (CSIR) in 2002 and subsequently upgraded to Senior Research Fellowship in 2004.
Won First Prizes at College and University level Chemistry Quiz Competitions.
Christina M. Woo, Shivajirao L. Gholap, Liang Lu, Miho Kaneko, Zhenwu Li, P.C. Ravikumar, and Seth B. Herzon, Development of Enantioselective Synthetic Routes to (–)-Kinamycin F and (–)-Lomaiviticin Aglycon. J. Am. Chem. Soc.2012, 134 (41), 17262-17273.
Lihua Yao, Bhaskar Pitta, P. C. Ravikumar, Matthew Purzycki, and Fraser F.Fleming, Transmissive Olefination Route to Putative "Morinol I" Lignans, J. Org. Chem.,2012, 77(7), 3651–3657.
Fraser F. Fleming, Wang Liu, Lihua Yao, Bhaskar Pitta, Matthew Purzycki, P. C. Ravikumar, Alkenenitrile Transmissive Olefination: Synthesis of the Putative Lignan “Morinol I”, Eur. J. Org. Chem., 2011, 34, 6843.
Fraser F. Fleming, Lihua Yao, P. C. Ravikumar, Lee Funk and Brian C. Shook, Nirile-Containing Pharmaceuticals: Efficacious role of the Nitrile Pharmacophore, J. Med. Chem., 2010, 53, 7902-7917.
Shivajirao L Gholap, Christina M. Woo, P. C. Ravikumar, Seth B. Herzon, Synthesis of the Fully Glycosylated Cyclohexenone Core of Lomaiviticin A, Org. Lett., 2009, 11, 4322-4325.
P. C. Ravikumar, Lihua Yao, Fraser F. Fleming, Allylic and Allenic Halide Synthesis via NbCl5- and NbBr5- Mediated Alkoxide Rearrangement. J. Org. Chem., 2009, 74, 7294-7299.For a commentary see: NbCl5/NbBr5-Mediated Alkoxide Rearrangements to Allylic and Allenic Halides. Paul Knochel and Andreas J Wagner, SYNFACTS, 2009, 12, 1394.
Fraser F. Fleming, P. C. Ravikumar, Lihua Yao, Direct Conversion of Aldehydes and Ketones to Allylic Halides by a NbX5-[3,3] Rearrangement, Synlett, 2009, 1077-1080.
Adusumilli Srikrishna, Ponneri C. Ravikumar, Hema S. Krishnan, The First Total Synthesis of Herbertenone A and Herberteneone B, Synthesis, 2008, 1527-1534.
A. Srikrishna, S. Ratna kumar, P. C. Ravikumar, Synthesis of (±)-12-Methoxy Herbertenediol methylether, Synth. Commun., 2007, 37, 4123-4140.
A. Srikrishna, R. Ramesh Babu, P. C. Ravikumar, A Regioselective Total Synthesis of Fungal Sesquiterpene (±)-Lagopodin A, Synlett, 2007, 655-657.
A. Srikrishna, P. C. Ravikumar, The First Total Synthesis of (±)-γ-Herbertenol, an herbertene isolated from a non-herbertus source, Synthesis, 2007, 65-74.
A. Srikrishna, P. C. Ravikumar, Structure revision of HM-3, an aromatic sesquiterpene isolated from phytopatogenic fungus Helicobasidium mompa. First Total Synthesis of HM-3 and HM-4, Tetrahedron, 2006, 62, 9393-9402.
A. Srikrishna, B. Vasantha Lakshmi, P. C. Ravikumar, The First Total Synthesis of (±) Lagopodin A, Tetrahedron Lett., 2006, 47, 1277-1281. (This Paper was the Second Most Hottest Paper of the first quarter of 2006)
A. Srikrishna, P. C. Ravikumar, Total Synthesis of HM-1 and HM-2, aromatic sesquiterpenes isolated from the phytopatogenic fungus Helicobasidium mompa. Structure revision of HM-2, Tetrahedron Lett., 2005, 46, 6105-6109.
Conferences And Symposia
Metallated Nitrile: Preferential SN2 Cyclizations of Allylic Chlorides, Wang Liu, Ping Lu, P. C. Ravikumar and Fraser F. Fleming. 240th American Chemical Society National Meeting, 22nd - 26th Aug 2010, Boston, USA.